Howe believes that Isak's exclusion has affected the team's morale and he won't tolerate anyone disrupting the harmony in the squad.
He said that the team has been disrupted by Isak's situation, which has caused unrest and distraction among the players.
Howe praised the players for their professionalism and dedication to training, but acknowledged that the team is struggling to cope with Isak's absence.
When asked if Isak could make a comeback for the team's Premier League opener against Aston Villa, Howe replied that he doesn't see it happening before that match.